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Tert-Butyldimethylsilyl chloride

Product Introduction

 Product Name  Tert-Butyldimethylsilyl chloride
 CAS  18162-48-6
 Applications 1. A common silylating and protecting reagent in organic synthesis, mainly used for selective protection of hydroxyl groups, amines, amides and thiols in molecules。
 
2. Widely applied in pharmaceutical synthesis, including prostaglandins, antibiotics, antiviral drugs, lipid-lowering drugs and nucleoside derivatives。
 
3. Used as a derivatization reagent for GC/MS analysis to improve the volatility and detection efficiency of samples。
 
4. Raw material for the preparation of various organosilicon intermediates and fine chemicals.
 Typical properties

  Appearance  Almost White Crystals
 Solubility  Soluble in common organic solvents; Reacts with water and   alcohols, sensitive to   moisture
 Melting Point  86-90 ℃
 Boiling Point  125 ℃
 Flash Point  53 ℃
 Relative Density (20 °C, water=1)  0.81
 Vapor Pressure (25 °C)  2 KPa
 Assay (Purity by GC)  ≥99.0%
 Product Name  Tert-Butyldimethylsilyl chloride
 CAS  18162-48-6
 Applications 1. A common silylating and protecting reagent in organic synthesis, mainly used for selective protection of hydroxyl groups, amines, amides and thiols in molecules。
 
2. Widely applied in pharmaceutical synthesis, including prostaglandins, antibiotics, antiviral drugs, lipid-lowering drugs and nucleoside derivatives。
 
3. Used as a derivatization reagent for GC/MS analysis to improve the volatility and detection efficiency of samples。
 
4. Raw material for the preparation of various organosilicon intermediates and fine chemicals.
 Typical properties

  Appearance  Almost White Crystals
 Solubility  Soluble in common organic solvents; Reacts with water and   alcohols, sensitive to   moisture
 Melting Point  86-90 ℃
 Boiling Point  125 ℃
 Flash Point  53 ℃
 Relative Density (20 °C, water=1)  0.81
 Vapor Pressure (25 °C)  2 KPa
 Assay (Purity by GC)  ≥99.0%
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